In words, the time rate of change of the partial derivative of the Lagrangian with respect to generalized velocity minus the partial derivative of the Lagrangian with respect to generalized coordinate is equal to the generalized force.
The first term in the equation is the time rate of change of generalized momentum, which is another name for the partial derivative of the Lagrangian with respect to generalized velocity. Evaluating the following derivative corresponding to a moving particle in a potential U,