Research Chien-Shiung Wu's contributions lie heavily in the realm of nuclear physics--specifically her research concerning beta decay. Chien-Shiung Wu was one of the first to confirm Enrico Fermi's Theory of Beta Decay In 1957, she successfully implemented an experiment confirming Tsung-Dao Lee and Chen Ning Yang's theory that the Law of Parity did not hold true during beta decay.  The Law of Parity stated that nature possesses fundamental symmetry and essentially 'cannot discern left from right.' Chien-Shiung Wu disproved this law using the beta decay of radioactive cobalt at temperatures near absolute zero.  This is often considered her most significant contribution to modern physics.