Long-Distance
Signaling by Action Potentials
Current conduction by wires, and neurons in the absence of action
potentials, is known as passive current flow. The rate of action
potential limits the flow of information within the nervous system.
This rate of action potential propagation along great distances is
determined by the passive and active current flow.
One way to improve passive current flow is to increase the diameter of
the axon to decrease the internal resistance to passive current flow.
Another way to improve the passive flow is to insulate the axonal
membrane with myelin. This reduces the amount of current that would
otherwise leak out of the axon and increases the distance that the
current can flow passively.
image:http://fig.cox.miami.edu/~cmallery/150/neuro/c7.48.8.node.ranvier.jpg
Myelination, aka axon
insulation, increases action potential conduction up to 150m/s compared
to 0.5-10m/s conduction velocities of unmyelnated axons!
Speedy delivery of current (information) along axons is also due to the
nodes of Ranvier. Nodes of Ranvier are gaps between insulated portions
of the axon. The gaps create a place where the current can flow out of
the axon so an action potential can be generated.
Action potentials are started at one end of the node, flow passively
through the myelinated axon, and pop out the other side to jump to the
next node. This jumping of action potentials is called saltatory.